SARS-CoV-2 in Atmospheric Particulate Matter: An Experimental Survey in the Province of Venice in Northern Italy대기 미립자 물질의 SARS-CoV-2: 이탈리아 북부 베니스 지방의 실험적 조사Article Published on 2022-08-022022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] 229E Air pollution Airborne transmission Analysis atmospheric collected Concentration coronavirus 229E COVID-19 fiber FIVE Infection Italy knowledge MOST Occurrence Particulate Particulate matter positive quartz sampling SARS-CoV-2 SARS-CoV-2 in air Spread Surveillance survey Transport Transport carrier. Venice virus detection was performed [DOI] 10.3390/ijerph19159462 PMC 바로가기 [Article Type] Article
Rapid Detection of SARS-CoV-2 Using Duplex Reverse Transcription-Multienzyme Isothermal Rapid Amplification in a Point-of-Care Testing현장 진료 테스트에서 이중 역전사-다효소 등온 급속 증폭을 사용한 SARS-CoV-2의 신속한 검출Cellular and Infection Microbiology Published on 2021-10-222022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] 229E 95% CI 95% confidence interval a low volume acute respiratory syndrome Adenovirus Amplicon amplicons amplification amplify buffer caused Concentration coronavirus coronavirus 229E cross-reaction detection diagnostics duplex multienzyme isothermal rapid amplification Efficacy extraction guanidinium human parainfluenza virus Influenza influenza A influenza A virus influenza B influenza B virus isothermal amplification lateral flow lateral flow dipstick limit of detection MERS MERS-CoV N gene National Negative predictive value nucleic acid nucleic acid test nucleic acid tests ORF1 ORF1ab ORF1ab gene Pathogens point-of-care testing Positive predictive value Precision Predictive value primer Primers probe probes qPCR Rapid reaction respiratory Respiratory pathogens respiratory syncytial virus RNA extraction SARS-CoV SARS-CoV-2 Severe acute respiratory syndrome specimen Spread suspected patient suspected patients Swab target temperature Testing virus Volume were used without RNA extraction [DOI] 10.3389/fcimb.2021.678703 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
A human coronavirus evolves antigenically to escape antibody immunity인간 코로나 바이러스는 항체 면역을 피하기 위해 항원 적으로 진화합니다.Research Article Published on 2021-04-082022-08-13 Journal: PLoS Pathogens [Category] Biology and Life Sciences, COVID-19, SARS, [키워드] 229E 229E strain 229E strains 229E viral strain 229E viruses accumulate anti-SARS-CoV-2 titer anti-SARS-CoV-2 titers antibody antibody immunity antigenic evolution common-cold comparable coronavirus coronavirus coronavirus 229E coronavirus vaccine Coronavirus vaccines Coronaviruses degrade elicited Evolution Hope Human coronavirus human coronavirus 229E human sera Hypothesis identify Immunity in some individuals Infection less Mutation neutralization neutralize Neutralizing titer neutralizing titers NTD occur Older other coronaviruses pace PROTECT question re-infect Re-infection Re-infections Receptor-binding domain Region SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccines seasonal coronavirus sera Spike protein strain Strains subsequent the RBD the receptor-binding domain titers vaccination variants of SARS-CoV-2 Viral viral evolution viral mutation Viral mutations viral spike viral strains virus virus viruses was collected [DOI] 10.1371/journal.ppat.1009453 PMC 바로가기 [Article Type] Research Article
Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients입원하지 않은 COVID-19 환자의 SARS-CoV-2 및 계절성 코로나바이러스에 대한 항체 반응Research Article Published on 2021-02-242022-09-10 Journal: mSphere [Category] MERS, 진단, 치료기술, 치료법, 치료제, [키워드] 229E addition addressed ADE antibody Antibody Response antibody response against Antibody responses Antibody-dependent enhancement antibody-dependent enhancement (ADE) Asymptomatic breadth conducted contribute coronavirus coronavirus 229E correlated Course COVID-19 cross-protection detect develop diagnostic diagnostic test difficulty Dilution disease experiments highlight Hospitalization human cell human cells Immunity individual infected individuals Infection involved majority marker Mild neutralization Neutralizing activity Neutralizing antibodies Neutralizing antibody response neutralizing antibody responses nucleocapsid Patient phenomenon positive predictor quantified question receptor binding site response S protein SARS-CoV-2 SARS-CoV-2 neutralization seasonal seasonal coronaviruses sera serological Serological assay serological survey Serum Neutralization Spike protein surrogate markers symptomatic targets the S protein the spike protein to define Vaccine development Virus neutralization western blot [DOI] 10.1128/mSphere.01145-20 PMC 바로가기 [Article Type] Research Article
Qualitative and Quantitative Analysis of Ukrainian Iris Species: A Fresh Look on Their Antioxidant Content and Biological ActivitiesArticle Published on 2020-10-082022-10-30 Journal: Molecules [Category] Coronavirus, MERS, [키워드] Iris rhizomes 229E activity analysis analyzed anti-allergic Anti-inflammatory anti-inflammatory activity antioxidant Biological caffeic acid Cancer cells Compound compounds content coronavirus 229E cytotoxic cytotoxic effect demonstrated evaluated examined exhibited expression Fresh gallic acid group highest HPLC-ABTS HPLC-DAD human neutrophils IRIS Iris sibirica limit marker methanol Nrf2 Phenolic compounds Qualitative quantification Quantitative standard reference UPLC–MS/MS [DOI] 10.3390/molecules25194588 PMC 바로가기 [Article Type] Article
Analysis of Covid-19 and non-Covid-19 viruses, including influenza viruses, to determine the influence of intensive preventive measures in JapanArticle Published on 2020-07-072022-11-01 Journal: Journal of Clinical Virology [Category] COVID-19, MERS, [키워드] addition analyzed Causative caused cold-like symptom collected coronavirus coronavirus 229E COVID-19 death detect determine FilmArray incidence infected patient Infection infection control Influenza influenza virus Influenza virus influenza viruses Intensive Japan métapneumovirus Multiplex PCR Nasopharyngeal swab objective OC43 Other Panel Panel analysis pathogen Patient patients PCR Prevalence prevalent preventive measure preventive measures respiratory Respiratory Coronavirus respiratory viruses Result reverse transcription PCR RT-PCR RT-PCR analysis SARS-CoV-2 SARS-CoV2 Spread Symptom virus virus viruses [DOI] 10.1016/j.jcv.2020.104543 PMC 바로가기 [Article Type] Article
Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronavirusesArticle Published on 2020-06-242022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Alpha ambient Applied microbiology approach coronavirus coronavirus 229E demonstrated dose effective Efficacy Efficiency expected eyes genomic germicidal HCoV-229E HCoV-OC43 Health human coronavirus human tissues inactivated inactivation Influenza virus kill limit limits Microbiology pathogen reduction in Regulatory SARS-CoV-2 ultraviolet light viral inactivation Viral transmission [DOI] 10.1038/s41598-020-67211-2 PMC 바로가기 [Article Type] Article
Genetic diversity and ecology of coronaviruses hosted by cave-dwelling bats in GabonArticle Published on 2020-04-302022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] activity alphacoronavirus alphacoronavirus analysis association bat bats betacoronavirus cave collected conducted coronavirus coronavirus 229E CoV CoV infection CoVs driving Ecology Factor FIVE Gabon HCoV-229E highlight Hipposidero Human Infection Microbiology Miniopterus non-human primate Prevalence Research rodents screened sequence significantly significantly higher wild animal wild animals zoonotic [DOI] 10.1038/s41598-020-64159-1 PMC 바로가기 [Article Type] Article
Viral nucleic acid analysis with PCR in lacrimal tissue and nasal swab samples of primary acquired nasolacrimal duct obstruction casesOriginal Research Article Published on 2019-10-212022-10-31 Journal: European Journal of Ophthalmology [Category] Coronavirus, [키워드] Adenovirus age Analysis Characteristics coronavirus coronavirus 229E diagnosed evaluate Factor HKU1 men mucosal nasal nasal swab NL63 nucleic acid nucleic acid extraction OC43 Pathogenesis Patient patients PCR polymerase chain polymerase chain reaction positive primary acquired nasolacrimal duct obstruction Qualitative respiratory syncytial virus statistically significant Swab tissue viral genome viral infection virus was performed women [DOI] 10.1177/1120672119882331 PMC 바로가기 [Article Type] Original Research Article
Crystal structure of the post‐fusion core of the Human coronavirus 229E spike protein at 1.86 Å resolutionResearch Papers Published on 2018-09-102022-10-27 Journal: Acta crystallographica. Section D [Category] Coronavirus, MERS, [키워드] addition Adults appear cause comparison Complete conserved coronavirus coronavirus 229E crystal structure electrostatic electrostatic interaction facilitate HCoV‐229E heptad repeat host cell host membranes Human human coronavirus hydrophobic hydrophobic interaction immune systems individual inhibit inhibitor Interaction involved MERS Mild Mortality opposite peptide polar post‐fusion core preserved Protein representing reveal S1 domain S2 domain SARS severe complication small molecule Spike protein structures subsequent surface potential upper respiratory infection virus was determined weakened X‐ray structure [DOI] 10.1107/S2059798318008318 PMC 바로가기 [Article Type] Research Papers